3-Hydroxy Midostaurin

Supplier MedChemExpress
Product # HY-108263-50 mg
CAS # 179237-49-1
Pricing 50 mg, USD $5500.0
Biological Activity 3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412[1].
Synonyms CGP52421
MWt 586.64
Formula C₃₅H₃₀N₄O₅
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