rac Ketorolac-[d4]
Labelled rac Ketorolac. Ketorolac, a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug. It shows inhibition of eicosanoid formation in HEL cells (COX-1) and LPS-stimulated Mono Mac 6 cells (COX-2), but does not significantly inhibit NO accumulation in supernatants of LPS-stimulated RAW 264.7 cells. It significantly inhibits thymidine incorporation of human osteoblasts (hOBs) upon 24 hours treatment in a dose-dependent manner, and inhibits proliferation and arrests cell cycle at G0/G1 phase in hOBs.
| Supplier | BOC Sciences |
|---|---|
| Product # | BLP-004019 |
| Pricing | Inquire |
| Cas | 1216451-53-4 |
| Molecular Weight | 259.29 |
| Molecular Formula | C15H9D4NO3 |
| Canonical SMILES | C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O |