ABT-100
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-119257-5 mg |
| CAS # | 450839-40-4 |
| Pricing | 5 mg, USD $400.0 |
| Biological Activity | ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity[1]. |
| Purity | 98.18% |
| MWt | 504.46 |
| Formula | C₂₇H₁₉F₃N₄O₃ |