ε-V1-2, ε-PKC Inhibitor

Supplier Creative Peptides
Product # P75001
Pricing Inquire
MolecularWeight 844
Sequence
  • One Letter Code: EAVSLKPT
  • Three Letter Code: H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Storage -20°C
Explanation This peptide is derived from residues 14-21 of protein kinase C C2 (εPKC C2). This peptide specifically inhibits εPKC by disrupting PKC binding to its receptor, RACK2. εPKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.
Reference
  • 1. Lamy, C. et al. Tetrahedron Lett 46, 6177 (2007).
  • 2. Brandman, R. et al. J. Biol. Chem. 282, 4113 (2007).
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