Melanocyte-Stimulating Hormone Receptor (MC1R) Antibody
MC1R Antibody is a Rabbit Polyclonal antibody against MC1R. This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.
Supplier | Abbexa Ltd. |
---|---|
Product # | abx002182-50UL |
Pricing | 50 µl USD $319.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | WB |
UniProt Primary AC | Q01726 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |