| Supplier |
Creative Peptides |
| Product # |
C15018 |
| Pricing |
Inquire
|
| MolecularWeight |
1717
|
| Sequence |
- One Letter Code: GRGDSGAASIKVAVSADR
- Three Letter Code: H-Gly-Arg-Gly-Asp-Ser-Gly-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.
|
| Reference |
- 1. Ohga, Y. et al. Biomater. 30, 6731 (2009).
- 2. Kasai, S. et al. Biopolymers Pept. Sci. 76, 27 (2004).
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