Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25)
Recombinant Human Antibody (VRC26.25) is capable of binding to HIV-1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody neutralized 57% of diverse clade 43 viral isolates and 70% of clade C isolates with remarkable potency.
Supplier | Creative Biolabs |
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Product # | PABL-140 |
Pricing | Inquiry |
Host | Human |
Target | HIV-1 |
Species Reactivity | HIV-1 |
Type | Human IgG1 |
Applications | WB, ELISA, Neut, FuncS |
Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |