Cyclo(-Arg-Gly-Asp-D-Phe-Lys)

Supplier Creative Peptides
Product # R04029
CAS # 161552-03-0
Pricing Inquire
Synonyms c(RGDfK)
MolecularFormula C27H42N9O7
MolecularWeight 603.68
Sequence
  • One Letter Code:Cyclo(-RGDfK)
  • Three Letter Code: Cyclo(Arg-Gly-Asp-Phe-Lys)
Storage Desiccate at -20°C
ShippingCondition Room temperature in continental US; may vary elsewhere.
Explanation cyclo[-Arg-Gly-Asp-D-Phe-Lys-]
BiologicalActivity Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface.
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