Supplier |
Creative Peptides |
Product # |
R04029 |
CAS # |
161552-03-0 |
Pricing |
Inquire
|
Synonyms |
c(RGDfK)
|
MolecularFormula |
C27H42N9O7
|
MolecularWeight |
603.68
|
Sequence |
- One Letter Code:Cyclo(-RGDfK)
- Three Letter Code: Cyclo(Arg-Gly-Asp-Phe-Lys)
|
Storage |
Desiccate at -20°C
|
ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
Explanation |
cyclo[-Arg-Gly-Asp-D-Phe-Lys-]
|
BiologicalActivity |
Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface.
|