Alsterpaullone
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108359-10 mM * 1 mL |
| CAS # | 237430-03-4 |
| Pricing | 10 mM * 1 mL, USD $726.0 |
| Synonyms | 9-Nitropaullone; NSC 705701 |
| MWt | 293.28 |
| Formula | C₁₆H₁₁N₃O₃ |
| Biological Activity | Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders[1]. |
| Purity | ≥98.0% |