Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate

Methyl 4-[(3-chloro-2-fluorophenyl)methyl]-1-piperazinecarboxylate is an intermediate in the synthesis of CK 1827452 (C544000), a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.

• Supplier: BOC Sciences
• Product #: BB060194
• Cas: 1309439-45-9
• Molecular Weight: 286.73
• Molecular Formula: C13H16ClFN2O2