N-[(2S)-1-amino-5-[(1-amino-2-chloroethylidene)amino]-1-oxopentan-2-yl]benzamide
Cl-amidine is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4. Cl-amidine induces apoptosis in cancer cells. Cl-Amidine prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model.
| Supplier | BOC Sciences |
|---|---|
| Product # | 913723-61-2 |
| Pricing | Inquire |
| Cas | 913723-61-2 |
| Molecular Weight | 310.78 |
| Molecular Formula | C14H19ClN4O2 |
| Canonical SMILES | C1=CC=C(C=C1)C(=O)NC(CCCN=C(CCl)N)C(=O)N |