CXCR2-IN-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-120878-10 mM * 1 mL |
| CAS # | 1838123-21-9 |
| Pricing | 10 mM * 1 mL, USD $440.0 |
| Biological Activity | CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. CXCR2-IN-2 inhibits human whole blood Gro-α induced CD11b expression with an IC50 of 0.04 μM[1]. |
| Purity | 99.35% |
| MWt | 414.9 |
| Formula | C₁₈H₂₃ClN₂O₅S |