CXCR2-IN-2

Supplier MedChemExpress
Product # HY-120878-10 mM * 1 mL
CAS # 1838123-21-9
Pricing 10 mM * 1 mL, USD $440.0
Biological Activity CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. CXCR2-IN-2 inhibits human whole blood Gro-α induced CD11b expression with an IC50 of 0.04 μM[1].
Purity 99.35%
MWt 414.9
Formula C₁₈H₂₃ClN₂O₅S
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