2-Chloro-3-methylpyrazine
2-Chloro-3-methylpyrazine (CAS# 95-58-9) is the derivative of Andrographolide(A637475) is a labdane diterpenoid (2). Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata (2). Andrographolide showed significant antihepatotoxic action in P. berghei K173-induced hepatic damage in M. natalensis(1). Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases (2). These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent.
| Supplier | BOC Sciences |
|---|---|
| Product # | BB041766 |
| Pricing | Inquire |
| Cas | 95-58-9 |
| Molecular Weight | 128.56 |
| Molecular Formula | C5H5ClN2 |
| Canonical SMILES | CC1=NC=CN=C1Cl |