GW806742X hydrochloride

Supplier MedChemExpress
Product # HY-112292A-5 mg
Pricing 5 mg, USD $60.0
Biological Activity GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 μM. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis[1][2].
Purity 98.77%
MWt 610.01
Formula C₂₅H₂₃ClF₃N₇O₄S
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