Tyk2-IN-5

Supplier MedChemExpress
Product # HY-111745-25 mg
CAS # 1797432-62-2
Pricing 25 mg, USD $1500.0
Biological Activity Tyk2-IN-5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα. Highly effective in inhibiting IFNγ production in a rat pharmacodynamics model and fully efficacious in a rat adjuvant arthritis model[1].
Purity 99.78%
MWt 434.43
Formula C₂₁H₁₉FN₈O₂
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