Human Anti-High mannose glycans Recombinant Antibody (clone 2G12)
Human monoclonal antibody (MAb) 2G12 efficiently neutralizes a broad range of HIV-1 primary isolates in vitro (1–3) and protects from in vivo viral challenge in macaques in combination with other antibodies (4–6). MAb 2G12 binds with high affinity to a unique, conserved epitope on the HIV-1 envelope that is formed by a cluster of N-linked, high-mannose glycan groups on the "silent" face of gp120.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-S0061-YC |
| Pricing | Inquiry |
| Host | Human |
| Target | High mannose glycans |
| Species Reactivity | HIV-1 |
| Type | Human IgG |
| Applications | ELISA, Neut |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |