CU-3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-121638-5 mg |
| CAS # | 861123-84-4 |
| Pricing | 5 mg, USD $460.0 |
| Biological Activity | CU-3 is the racemate of (5Z,2E)-CU-3. (5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells[1]. |
| MWt | 392.47 |
| Formula | C₁₆H₁₂N₂O₄S₃ |