K-Ras ligand-Linker Conjugate 1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-129775 |
| Pricing | inquire |
| Biological Activity | K-Ras ligand-Linker Conjugate 1 incorporates a ligand for K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 1 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1]. |
| MWt | 826.94 |
| Formula | C₄₃H₅₄N₈O₉ |