NKL 22
Supplier | MedChemExpress |
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Product # | HY-100384-50 mg |
CAS # | 537034-15-4 |
Pricing | 50 mg, USD $240.0 |
Biological Activity | NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice[1][2][3]. |
MWt | 325.4 |
Formula | C₁₉H₂₃N₃O₂ |