eIF4A3-IN-1

Supplier MedChemExpress
Product # HY-101513-5 mg
CAS # 2095486-67-0
Pricing 5 mg, USD $480.0
Biological Activity eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD[1].
Purity 99.70%
MWt 588.88
Formula C₂₉H₂₃BrClN₅O₂
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