Human Anti-ERBB2 Recombinant Antibody (clone Pertuzumab, 2C4); scFv Fragment

Recombinant Humanized Antibody (Pertuzumab, 2C4) scFv Fragment is specific to ERBB2 ECD, expressed in E. coli. The pertuzumab binding epitope overlaps with the ErbB2 ECD homodimer interface; thus, bound pertuzumab sterically prevents the dimerization arm from reaching the C-shaped pocket of the other ErbB2.
Supplier Creative Biolabs
Product # PSBC-158
Pricing Inquiry
Host Human
Target ERBB2
Species Reactivity Human
Type Human scFv
Applications IP, Neut
Storage Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
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