Human Anti-ERBB2 Recombinant Antibody (clone Pertuzumab, 2C4); scFv Fragment
Recombinant Humanized Antibody (Pertuzumab, 2C4) scFv Fragment is specific to ERBB2 ECD, expressed in E. coli. The pertuzumab binding epitope overlaps with the ErbB2 ECD homodimer interface; thus, bound pertuzumab sterically prevents the dimerization arm from reaching the C-shaped pocket of the other ErbB2.
Supplier | Creative Biolabs |
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Product # | PSBC-158 |
Pricing | Inquiry |
Host | Human |
Target | ERBB2 |
Species Reactivity | Human |
Type | Human scFv |
Applications | IP, Neut |
Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |