T-Box Transcription Factor TBX21 (TBX21) Antibody

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

• Supplier: Abbexa Ltd.
• Product #: abx028047-400UL
• Clonality: Polyclonal
• Conjugation: Unconjugated
• Host: Rabbit
• Tested Applications: ELISA, WB, IF/ICC
• UniProt Primary AC: Q9UL17
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.