Z-Leu-Arg-7-Amino-4-Methylcoumarin

Z-Leu-Arg-7-Amino-4-Methylcoumarin is a fluorescent substrate for cathepsin L, S, and V, human tissue kallikrein and the falcipains I-III. It is the preferred substrate for falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design. It is used to detect cathepsin K, an enzyme involved in osteoclast bone resorption.

• Supplier: BOC Sciences
• Product #: BAT-015242
• Cas: 156192-32-4
• Molecular Weight: 578.66
• Molecular Formula: C30H38N6O6
• Canonical SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)OCC3=CC=CC=C3