anti-Fcer1g immunotoxin 84.1C (IgG)-RTA
This immunotoxin was achieved by conjugating/fusing the Anti-Fcer1g monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to surface IgE-expressing cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of periodic (seasonal) allergic.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AGTO-L015R |
| Pricing | Inquiry |
| Applications | This product is suitable for use in cytotoxicity assay, functional assay and immunotherapy. |
| Host | Rat |
| Target | Fcer1g |
| Species Reactivity | Mouse |