KU-55933
KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. KU‑55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy‑initiating kinase ULK1 and results in a significant decrease of autophagy.
Supplier | Selleck Chemicals |
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Product # | S1092 |
Sku # | S1092-5mg |
Pricing | 5mg, $70.00 |
Citations for this product:
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bioRxiv - Molecular Biology 2021Quote: ... or 15 μM KU-55933 (Selleck Chemicals, #S1092) was added 1 hour prior to irradiation ...
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bioRxiv - Cell Biology 2022Quote: ... ATM: 10 µM KU-55933 (Selleck Chemicals: S1092), Chk1 ...