Berberine chloride hydrate
![](https://image.labshake.com/supplier-product/471d3a2a-073f-4b25-a7de-2da1c79248d6/e39d9713-e637-4722-a4ce-c3b5b28d8088.png)
Berberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
Supplier | Selleck Chemicals |
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Product # | S5967 |
Sku # | S5967-1g |
Pricing | 1g, $970.00 |