8-Aminoadenine
8-Aminoadenine is an adenine receptor agonist with Ki value of 0.0341 μM in HEK293 cells expressing an adenine binding site. It shows 190-fold increased potency at the human binding site over the rat adenine receptor. It inhibits adenine uptake and isoproterenol-stimulated cAMP accumulation. It may be used in the synthetic preparation of purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. It is important in regulating myocardial oxygen consumption and coronary blood flow. It may take part in inflammation and immune responses.
| Supplier | BOC Sciences |
|---|---|
| Product # | 28128-33-8 |
| Pricing | Inquire |
| Cas | 28128-33-8 |
| Molecular Weight | 150.14 |
| Molecular Formula | C5H6N6 |
| Canonical SMILES | C1=NC2=C(C(=N1)N)NC(=N2)N |