UDP-Glucuronosyltransferase 1-1 (UGT1A1) Antibody

UGT1A1 Antibody is a Rabbit Polyclonal antibody against UGT1A1. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
Supplier Abbexa Ltd.
Product # abx004726-20UL
Pricing 20 µl USD $203.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IHC, IF/ICC
UniProt Primary AC P22309
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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