Interleukin 12 Receptor Beta 1 (IL12RB1) Antibody
IL12RB1 Antibody is a Rabbit Polyclonal antibody against IL12RB1. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx001549-50UL |
| Pricing | 50 µl USD $319.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB |
| UniProt Primary AC | P42701 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |