PROTAC CDK9 degrader-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112811 |
| CAS # | 2435721-30-3 |
| Pricing | inquire |
| Biological Activity | PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1]. |
| MWt | 748.74 |
| Formula | C₃₉H₃₆N₆O₁₀ |