Hck-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125028-10 mM * 1 mL |
| CAS # | 1473404-51-1 |
| Pricing | 10 mM * 1 mL, USD $385.0 |
| Biological Activity | Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity[1]. |
| Purity | ≥98.0% |
| MWt | 402.81 |
| Formula | C₁₆H₁₁ClN₆O₃S |