Pozanicline dihydrochloride

Supplier MedChemExpress
Product # HY-110160-5 mg
CAS # 161416-61-1
Pricing 5 mg, USD $345.0
Synonyms ABT-089 dihydrochloride
MWt 265.18
Formula C₁₁H₁₈Cl₂N₂O
Biological Activity Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAChR with a Ki of 17 nM while binding to α7 nAChR is insignificant[2].
Purity ≥99.0%
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