Pozanicline dihydrochloride
Supplier | MedChemExpress |
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Product # | HY-110160-5 mg |
CAS # | 161416-61-1 |
Pricing | 5 mg, USD $345.0 |
Synonyms | ABT-089 dihydrochloride |
MWt | 265.18 |
Formula | C₁₁H₁₈Cl₂N₂O |
Biological Activity | Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline is an α4β2-selective nAChR agonist, which binds to rat brain α4β2 nAChR with a Ki of 17 nM while binding to α7 nAChR is insignificant[2]. |
Purity | ≥99.0% |