Seco Rapamycin (sodium salt)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin which is a natural macrolide immunosuppressant. Seco-rapamycin inhibits the ChT-L (D) and PGPH (E) peptidases, and activate the T-L (F) peptidase and poorly activates mTOR.
IC50: ChT-L
IC50: ChT-L
Supplier | BOC Sciences |
---|---|
Product # | 148554-65-8 |
Pricing | Inquire |
Cas | 148554-65-8 |
Molecular Weight | 936.15 |
Molecular Formula | C51H78NNaO13 |
Canonical SMILES | CC1CCC(OC1(C(=O)C(=O)N2CCCCC2C(=O)[O-])O)CC(C(=CC=CC=CC(C)CC(C)C(=O)C(C(C(=CC(C)C(=O)C=CC(C)CC3CCC(C(C3)OC)O)C)O)OC)C)OC.[Na+] |