ZLDI-8

Supplier MedChemExpress
Product # HY-123931-100 mg
CAS # 667880-38-8
Pricing 100 mg, USD $2250.0
Biological Activity ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 μM and a Ki of 26.22 μM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 μM[1][2].
Purity 98.53%
MWt 433.52
Formula C₂₄H₂₃N₃O₃S
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