pimelyl-[acyl-carrier protein] methyl ester esterase

Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains. Even though the enzyme can interact with coenzyme A thioesters, the in vivo role of the enzyme is to hydrolyse the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalysed by the fatty acid elongation enzymes.

• Supplier: Creative Enzymes
• Product #: EXWM-3514