Autocamtide-3 Derived Inhibitory Peptide(AC3-I); CaMKII Inhibitor, myristoylated

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Supplier Creative Peptides
Product # X21139
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MolecularWeight 1689.2
Sequence
  • One Letter Code: Myr-KKALHRQEAVDAL
  • Three Letter Code: Myr-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Storage -20°C
Explanation This is a myristoylated form of Autocamtide-3-Derived Inhibitory Peptide (AC3-I), a highly specific inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII) that is resistant to proteolysis. AC3-I is derived from Autocamtide-3, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.
Reference Chen, HX. et al. J Neurophysiol 85, 1368 (2001).
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