C57BL/6J-Ikbkbem1 Mouse
The Ikbkb gene is located on mouse chromosome 8. Twenty one exons are identified, with the ATG start codon in exon 2 and the TGA stop codon in exon 21. Exon 4 will be selected as target site. Cas9 and gRNA will be co-injected into fertilized eggs for KO mouse production.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | DMM-001200 |
| Pricing | Inquiry |
| Synonyms | AI132552, IKK, IKK-, IKK-2, IKK-be, IKK-beta, IKK2, IKKbe, IKKbeta |
| Category | Mouse Models |
| disease type | T2DM |
| Strain Name | C57BL/6J-Ikbkbem1 |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Diabetes |
| Target Name | Ikbkb (Lethal gene) |
| Gene ID | 16150 |