Interleukin 10 (IL10) Antibody
The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Supplier | Abbexa Ltd. |
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Product # | abx034229-80UL |
Pricing | 80 µl USD $290.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB, IHC, FCM |
UniProt Primary AC | P22301 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |