5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite

5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a uridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
Supplier BOC Sciences
Product # BRP-00413
Pricing Inquire
Cas 2360826-71-5
Molecular Weight 902.03
Molecular Formula C46H52N3O10PS2
Canonical SMILES O=C(SCCSP(OC1C(OC(N2C=CC(=O)NC2=O)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6CCCC6)C=7C=CC=CC7
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