RG108
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13642-10 mg |
| CAS # | 48208-26-0 |
| Pricing | 10 mg, USD $72.0 |
| Synonyms | N-Phthalyl-L-tryptophan |
| MWt | 334.33 |
| Formula | C₁₉H₁₄N₂O₄ |
| Biological Activity | RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. |
| Purity | 99.81% |