Rucaparib phosphate
Rucaparib is a tricyclic indole poly(ADP-ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antitumor activities. Rucaparib selectively binds to PARP1 and inhibits PARP1-mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. This may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiotherapy.
| Supplier | Alfa Cytology |
|---|---|
| Product # | BC0068 |
| Pricing | 25.0 mg, 50.0 mg, 100.0 mg, 200.0 mg, 500.0 mg, 1.0 g, 2.0 g, 5.0 g, 10.0 g, inquire |