ACPT-1
ACPT-1 is a blood-brain barrier permeable agonist of group III metabotropic glutamate (mGlu) receptors. In primary neuronal cell cultures ACPT-I (1-200 μM), applied 30 min-3 h after starting the exposure to KA (150 μM), significantly attenuated the KA-induced LDH release, increased cell viability, and inhibited caspase-3 activity both in cortical and hippocampal cell cultures.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD653 |
| CAS # | 194918-76-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | ACPT-1; ACPT 1; ACPT1; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C8H11NO6 |
| Exact Mass | 217.0586 |
| Molecular Weight | 217.17 |
| Elemental Analysis | C, 44.24; H, 5.11; N, 6.45; O, 44.20 |
| IUPAC/Chemical Name | (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid |
| InChi Key | FERIKTBTNCSGJS-KIGHRTHISA-N |
| InChi Code | InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8- |
| SMILES Code | O=C([C@@]1(N)C[C@@H](C(O)=O)[C@@H](C(O)=O)C1)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.03.00 |
| Availability | 2 Weeks |