A-317491
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15568-10 mM * 1 mL |
| CAS # | 475205-49-3 |
| Pricing | 10 mM * 1 mL, USD $152.0 |
| Biological Activity | A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux[1][2]. |
| Purity | 99.18% |
| MWt | 565.57 |
| Formula | C₃₃H₂₇NO₈ |