MSA-2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136927-10 mM * 1 mL |
| CAS # | 129425-81-6 |
| Pricing | 10 mM * 1 mL, USD $385.0 |
| Biological Activity | MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. MSA-2 shows EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models[1][2]. |
| Purity | 98.79% |
| MWt | 294.32 |
| Formula | C₁₄H₁₄O₅S |