(Z)-4EGI-1
(Z)-4EGI-1, the Z-isomer of 4EGI-1, is an inhibitor of eIF4E/eIF4G interaction and translation initiation and has anticancer activity. It effectively binds to eIF4E with an IC50 of 43.5 μM and a Kd of 8.74 μM.
| Supplier | BOC Sciences |
|---|---|
| Product # | 901787-88-0 |
| Pricing | Inquire |
| Cas | 901787-88-0 |
| Molecular Weight | 451.28 |
| Molecular Formula | C18H12Cl2N4O4S |
| Canonical SMILES | C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-] |