2-Methoxyestradiol
Supplier | MedChemExpress |
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Product # | HY-12033-10 mM * 1 mL |
CAS # | 362-07-2 |
Pricing | 10 mM * 1 mL, USD $55.0 |
Synonyms | 2-ME2; NSC-659853 |
MWt | 302.41 |
Formula | C₁₉H₂₆O₃ |
Biological Activity | 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6]. |
Purity | 99.82% |