2-Methoxyestradiol

Supplier MedChemExpress
Product # HY-12033-10 mM * 1 mL
CAS # 362-07-2
Pricing 10 mM * 1 mL, USD $55.0
Synonyms 2-ME2; NSC-659853
MWt 302.41
Formula C₁₉H₂₆O₃
Biological Activity 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
Purity 99.82%
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