LNA-G(dmf)-CE Phosphoramidite

LNA-G(dmf)-CE Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a locked nucleic acid (LNA) backbone with a guanine base modified with a dimethylformamide (dmf) group. Additionally, it contains a 5'-cyanoethyl (CE) phosphoramidite functionality for controlled addition during synthesis. LNAs are known for their enhanced hybridization properties and stability, and the dmf modification further enhances these characteristics. This phosphoramidite is valuable in molecular biology research for applications requiring high specificity and affinity, such as antisense oligonucleotide therapy, SNP detection, and diagnostic assays.
Supplier BOC Sciences
Product # BRP-00390
Pricing Inquire
Cas 709641-79-2
Molecular Weight 852.91
Molecular Formula C44H53N8O8P
Canonical SMILES CC(C)N(C(C)C)P(OCCC#N)OC1C2C(OC1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=NC7=C6N=C(NC7=O)N=CN(C)C
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