Losartan Carboxylic Acid
EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. It is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively.
| Supplier | BOC Sciences |
|---|---|
| Product # | 124750-92-1 |
| Pricing | Inquire |
| Cas | 124750-92-1 |
| Molecular Weight | 436.89 |
| Molecular Formula | C22H21ClN6O2 |
| Canonical SMILES | [H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(CN4C(C(O)=O)=C(Cl)N=C4CCCC)C=C3 |