(S)-dimethyl 2-(4-(4-oxobutyl)benzamido)pentanedioate

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(S)-dimethyl 2-(4-(4-oxobutyl)benzamido)pentanedioate is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis.

Supplier	BOC Sciences
Product #	1081974-98-2
Pricing	Inquire
Cas	1081974-98-2
Molecular Weight	349.38
Molecular Formula	C18H23NO6

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