Defensin 5 (human)

Defensin 5 (human), a key regulator of gut microbiota homeostasis, shows microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine. The reduction or loss of HD 5 release from intestinal mucosa is associated with susceptibility to enteric pathogens, changes in microbial composition, and disruption of intestinal immune homeostasis. As a biomarker, it can be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn's colitis (high levels of HD 5).

• Supplier: BOC Sciences
• Product #: BAT-014814
• Molecular Weight: 3582.18
• Molecular Formula: C144H238N50O45S6
• Canonical SMILES: CCC(C)C1C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)N3)CCCNC(=N)N)C(C)O)CCCNC(=N)N)NC(=O)C(NC(=O)C(CSSCC(NC2=O)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)C(C(C)O)NC(=O)C(C)N)CC4=CC=C(C=C4)O)C(=O)NC(C(=O)N1)CCC(=O)O)C(C)C)CO)CC(C)C)CO)CCC(=O)O)CCCNC(=N)N)C(C)O)C)CC(C)C)CCCNC(=N)N)CC5=CC=C(C=C5)O)CC(C)C)CCCNC(=N)N)CO